ChromSmart^®

ChromSmart^® is designed to improve the productivity, consistency and usability of chromatography separation processes.  The system combines equipment automation with reasoning over data.  Data can include sample property information and real-time time measurements (UV, pressure, temperature, etc.).  Based upon this data ChromSmart^® can make decisions and implement experiments.  Applications include data analysis for high-throughput environments,  automation of the method development process for analytical laboratories, and walk-up/open-access systems for synthetic laboratory environments.      

Key Features and Benefits

• Increase productivity and consistency by combining data reasoning and equipment automation.
• Simplify interfaces for separation and reduce the burden of users. 
• Integrates with existing HPLC equipment and software, including column switchers.
• Controls method and equipment parameters, including pumps, detectors, automatic column switchers, and thermostats.
• Automatic equipment, column, and method monitoring.

Applied Modeling

• Apply both rule-based/heuristic models and empirical/physical models to analyze data.
• Incorporate flow sheet based decision trees for data reasoning and equipment control. 

Data Reasoning and Analysis

• In-method and post-method data analysis.
• Real-time, on-line in-method data-analysis of the chromatogram, temperature, and pressure. 
• Post-method data-analysis of experimental chromatograms by expert-system technology recommends experimental method conditions. 
• By evaluating the current and past chromatographic data, the recommendation uses real-time expert rules to optimize the HPLC separation and may pursue new lines of reasoning with the dynamic planning engine.

Custom Solutions

• Add custom knowledge to the system in the form of decision trees.  Click here for a brief description on automating rules of thumb. 
• Implement specific method development strategies, sample analysis and data reasoning.
• Add knowledge in the forms of rules-of-thumb, physical models, or historical data analysis.
• Include in-method data analysis i.e. data analysis during an active experiment
• Include post-method data analysis i.e. analyze data (chromatogram, peaks, etc.) at the conclusion of an experiment.
• Custom equipment and user interfaces to multiple equipment vendors.
• The real-time dynamic planning engine and intelligent decision tree technology within ChromSmart® can be extended to other types of analyses such as gas spectroscopy, mass spectroscopy, etc.